Ultrasound-enhanced thrombolysis in acute ischemic stroke: Potential, failures, and safety
نویسندگان
چکیده
منابع مشابه
Thrombolysis in acute ischemic stroke.
The administration of rt-PA to patients with acute ischemic stroke can result in improved functional outcomes. The safe and effective use of rt-PA in routine medical practice requires that patients seek help early, have a well-defined onset of their symptoms, be carefully examined for contraindications to rt-PA, receive a CT scan and interpretation to exclude hemorrhage, and receive the drug wi...
متن کاملQuantification of target population for ultrasound enhanced thrombolysis in acute ischemic stroke.
BACKGROUND AND PURPOSE Insonation of the occluded target vessel (sonothrombolysis) has been reported to increase the effect of intravenous thrombolysis in ischemic stroke. Its use has predominantly been described in middle cerebral artery (MCA) occlusions. Sufficient insonation conditions are a mandatory precondition. The impact of these limitations on eligibility rates for sonothrombolysis has...
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Introduction: Swallowing dysfunction complicates acute strokes in 25-32% of cases and directly affects patientschr('39') prognosis and recovery. Dysphagia complicates the course of acute strokes through its potential of the development of chest infection, nutritional problems, and dehydration. Dysphagia is also an independent predictor of respiratory morbidity and mortality in acute stroke. In...
متن کاملTrials of Thrombolysis in Acute Ischemic Stroke
Background and Purpose—Controversy regarding the risks and benefits of thrombolysis has not been helped by the perception that some trials were “positive” and others “negative” on their primary outcome measure of either “good” or “poor” functional outcome. We wondered whether the definition of good or poor functional outcome might have contributed to this perception, and what effect altering th...
متن کاملIntraarterial thrombolysis trials in acute ischemic stroke.
Stroke is a common cause of death and disability in industrialized nations. Technical advances and the increased availability of noninvasive brain imaging techniques have permitted precise and early diagnosis of acute cerebral ischemia. This has made emergent thrombolytic therapy for rapid restoration of cerebral perfusion increasingly possible. Herein, the authors present a review of the clini...
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ژورنال
عنوان ژورنال: Neurotherapeutics
سال: 2007
ISSN: 1933-7213,1878-7479
DOI: 10.1016/j.nurt.2007.05.012